Spindle orientation and asymmetric cell fate
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چکیده
منابع مشابه
Spindle orientation and asymmetric cell fate
Every organism begins as a single cell. Yet, in multicellular organisms, the progeny of that cell form a dazzling assortment of cell types. Generation of this diversity relies on asymmetric divisions. In contrast with symmetric divisions, which faithfully duplicate the characteristics of the parent cell, asymmetric divisions create two daughters that have different fates or identities. Asymmetr...
متن کاملREV IEW Spindle orientation during asymmetric cell division
Development of a multicellular organism from a fertilized egg depends on a precise balance between symmetric cell divisions to expand the pool of similar cells, and asymmetric cell divisions to create cell-type diversity. Spindle orientation can influence the generation of symmetric or asymmetric cell fates depending on how it is coupled to cell-intrinsic polarity cues, or how it is positioned ...
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ژورنال
عنوان ژورنال: Cell
سال: 1995
ISSN: 0092-8674
DOI: 10.1016/0092-8674(95)90022-5